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SDS
小鼠肺表面活性物質(zhì)關(guān)聯(lián)蛋白D(SPD)酶聯(lián)免疫吸附試劑盒
Catalog #: E03S0170
Sample Type: Biological samples

 

Other Names

Mouse Pulmonary Surfactant Associated Protein D ELISA kit

SPD; SFTPD; COLEC7; PSP-D; SFTP4; SP-D; Pulmonary Surfactant Protein D; Collectin-7; Lung surfactant protein D.

Research Area

Signal transduction, Cardiovascular, Cancer, Metabolism

Background

Surfactant protein D contributes to the lung's defense against inhaled microorganisms. It's a calcium ion dependent carbohydrate binding protein and is structurally similar to other C type mammalian lectins, such as conglutinin and SPA. It has a molecular size of approximately 37-43kDa in its reduced state, 620kDa in non dissociating conditions. Surfactant protein D enhances the production of oxygen radicals by rat alveolar macrophages and regulates some actions of SPA, which is the most abundant surfactant protein. Surfactant protein D is synthesized and secreted by alveolar epithelial type II cells.