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SDS
小鼠血管生成素相關(guān)蛋白6(ANGPTL6)酶聯(lián)免疫吸附試劑盒
Catalog #: E03A1446
Sample Type: Biological samples

 

Other Names

Mouse Angiopoietin related protein 6 ELISA kit

ANGPTL6; ARP5; AGF; Angiopoietin-Related Protein 5; Angiopoietin-related growth factor

Research Area

Cardiovascular, Signal transduction, Metabolism

Background

Angptl6 (angiopoietin-like 6) is a 470 amino acid secreted protein that contains one fibrinogen C-terminal domain and is a member of the angiopoietin-like family. Expressed abundantly in liver and present at lower levels in testis, kidney, heart, brain and lung, Angptl6 plays a role in wound healing and is also thought to promote neovascularization and enhance the chemotactic activity of endothelial cells. Additionally, Angptl6 may be involved in epidermal proliferation, remodeling and regeneration and may be able to counteract obesity by increasing energy expenditure. Human Angptl6 shares 74% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding Angptl6 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).