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SDS
Bovine Thrombin ELISA kit
Catalog #: E11T0084

 

Other Names

Activation peptide fragment 1; Activation peptide fragment 2; Coagulation factor II; FII; Prothrombin; Thrombin heavy chain; Thrombin light chain

Research Area

Signal transduction, Cell Biology, Cardiovascular

Background

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.