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SDS
兔髓分化因子88(MyD88)酶聯(lián)免疫吸附試劑盒
Catalog #: E04M0411
Sample Type: Biological samples

 

Other Names

Rabbit Myeloid differentiation primary response protein MyD88(MYD88) ELISA kit

Myeloid Differentiation Primary Response Gene 88

Research Area

Immunology, Cardiovascular, Signal transduction

Background

Myeloid differentiation primary response gene 88 (MYD88) is a protein that, in humans, is encoded by the MYD88 gene.The human ortholog MYD88 seems to function similarly to mice, since the immunological phenotype of human cells deficient in MYD88 is similar to cells from MyD88 deficient mice. However, available evidence suggests that MYD88 is dispensable for human resistance to common viral infections and to all but a few pyogenic bacterial infections, demonstrating a major difference between mouse and human immune responses.Mutation in MYD88 at position 265 leading to a change from leucine to proline have been identified in many human lymphomas including ABC subtype of diffuse large B-cell lymphoma and Waldenstrom's macroglobulinemia.